OUR VISION
Our Background.
Mologic has, when you add it up, hundreds of years’ experience in applying the fundamental research behind diagnostic development for healthcare. That’s a lot of hard graft in industry and academia, and that’s the foundation of our successes.
Mologic have a proud history in forming lasting partnerships, both academic and commercial. Our collaboration with Newcastle University, in particular with Rob Edwards and his colleagues, has resulted in a Lateral Flow product we are excited to bring to your field. Blackgrass can cause heavy yield loss, so obtaining clear information on non target site herbicide resistance via a quick and simple test provides cost and time savings, empowering the farm to make informed decisions. Our research is advancing towards extending the portfolio of innovative agricultural diagnostic devices, so look out for Mologic!
Mologic – Big in tiny science
Newcastle University “Our Vision”
The development of a herbicide resistance diagnostic for blackgrass is founded on 20 years of research into the underpinning science of the chemical control of this weed carried out by Rob Edwards’ research group (see references). As part of the current AHDB/BBSRC funded Blackgrass Resistance Initiative, we have prioritized realizing the outputs of this research into practical tools that can assist the UK arable farming industry in dealing with its current number 1 agronomic problem. Working with our commercial partner Mologic, this diagnostic technology is a world first in ‘on farm’ technologies that give agronomists and farmers a real measure of the degree of non-target site herbicide resistance in their blackgrass populations. We look forward to working with the industry in developing new weed management and decision tools based on access to the underpinning science of resistance.
Peer-reviewed papers on blackgrass research from the Edwards group
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Goldberg-Cavalleri, A., Tétard-Jones, C., Wortley , D.J., , Onkokesung, N., Brazier-Hicks, M. and Edwards, R. (2018) Glutathione transferases associated with non-target site resistance to herbicides in blackgrass (Alopecurus myosuroides). Weed Science. In press Special edition linked to WSSA Symposium, Arlington Feb 2018
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Tétard-Jones, C., Sabbadin, F., Moss, S, Hull, R., Neve, P. and Edwards, R. (2018)
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Changes in the proteome of the problem weed blackgrass correlating with multiple herbicide resistance. Plant Journal., DOI:10.1111/tpj.13892
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Gressel, J. and Edwards, R. (2018) Innovative crop protection for 21st century food security. Pest Management Science. 74, 779-780.
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Sabbadin, F., Glover, R., Stafford, R., Rozado-Aguirre, Z., Boonham, N., Adams, I., Mumford, R. and Edwards, R. (2017) Transcriptome sequencing identifies novel persistent viruses in herbicide resistant wild-grasses. Scientific Reports. 7, 49187. DoI: 10.1038/srep41987
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Tetard-Jones, C. and Edwards, R. (2015) Potential roles for microbial endophytes in herbicide tolerance in plants. Pesticide Management Science. 72, 203-209.
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Edwards, R. and Hannah, M. (2014) Focus on Weed Control. Plant Physiology. 166, 1-3.
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Cummins, I., Wortley D.J., Sabbadin, F., He, Z., Coxon, C.R., Straker, H.E.,
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J.D., Knight, K., Edwards, L.A., Hughes, D Kaundun. S-S., Hutchings, S-J., Steel, P.G., and Edwards, R. (2013) A key role for a glutathione transferase in multiple herbicide resistance in grass weeds. Proceedings National Academy of Science (USA) 110, 5812-5817.Sellars
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Cummins, I. and Edwards, R. (2010) The biochemistry of herbicide resistance in weeds. Outlooks on Pest Management. 21, 73-77.
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Cummins, I. , Bryant, D.N. and Edwards, R. (2009) Safener responsiveness and multiple herbicide resistance in the weed black-grass (Alopecurus myosuroides). Plant Biotechnology Journal. 7, 807-820.
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Cummins, I. and Edwards, R. (2004) Purification and cloning of an esterase from the weed black-grass (Alopecurus myosuroides), which bioactivates aryloxyphenoxypropionate herbicides. Plant Journal. 39, 894-904.
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Cummins, I., Cole, D. J. and Edwards, R. (1999) A role for glutathione transferases functioning as glutathione peroxidases in resistance to multiple herbicides in black-grass. Plant Journal. 18, 285-292.
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Cummins, I., Moss, S., Cole, D. J. and Edwards, R. (1997) Glutathione transferases in herbicide-resistant and herbicide-susceptible black-grass (Alopecurus
